Kyowa Expert Shares Views on Dipeptide Applications, Benefits of Glutathione at Nutritional Summit

Dr. Toshikazu Kamiya Highlights New Fermentation Technologies

Singapore, August 1, 2016 – Ingredient manufacturers are discovering unique ways to create nutraceutical values using innovative fermentation technologies.
That was the message shared by Dr. Toshikazu Kamiya at the recent Nutraceutical and Functional Food Asia Pacific Summit in Singapore. Dr. Kamiya, research fellow for Kyowa Hakko Bio, talked on how amino acids, peptides and oligosaccharides are being leveraged for better nutraceutical values.
Dr. Kamiya shared recent findings on the health benefits of oral glutathione supplementation. Specifically, he discussed how Kyowa’s Setria® Glutathione has been shown to replenish the body’s reserves, which may be depleted by poor lifestyle choices, natural aging and stress.* The fermentation process, he said, is the key to creating glutathione that is high purity and high quality.*
“As the most abundant antioxidant in the human body, glutathione is critical to the protection and overall health of organs and cells,” Dr. Kamiya said. “Glutathione already is used in many nutraceutical applications, including those for skin whitening and liver protection. It shows great promise for continued development and application in nutraceutical formulations.”
The presentation also covered the physical property of dipeptides and their applications. Kyowa manufactures Sustamine® L-Alanyl-L-Glutamine, a dipeptide of alanine and glutamine, which has superior solubility and stability in water as compared to.* Again, fermentation is what makes dipeptides like Sustamine® effective in enhancing recovery, building immune support and increasing metabolic rates.* 
“Kyowa Hakko Bio uses a proprietary dipeptide fermentation technology to produce L-Alanyl-L-Glutamine from glucose,” he said. “The end product – Sustamine® – is water soluble, making it a perfect ingredient for sports nutrition drinks, powders and supplements. It also has clinical applications for rehydration, as well as parenteral and enteral nutrition.”
Dr. Kamiya also spoke on the use of amino acids for wound healing and the functional roles of oligosaccharides. His presentation was part of the larger NFFAP Summit, held in early July. The conference provides information on “authoritative interpretation on market entry and supervision regulations for functional food in the main Asia-Pacific region.”

About Setria® Glutathione

Setria® Glutathione, manufactured by Kyowa Hakko Bio Co., Ltd., is a clinically studied and patented form of glutathione that, when taken orally1, has been shown to replenish the body's reserves, which may be depleted as a result of poor lifestyle choices, stress or natural aging. Called the "master antioxidant," glutathione helps protect cells in the body from the damaging effects of oxidative stress and toxins. Setria® Glutathione is manufactured through a patented fermentation process to yield high purity and high quality, is vegetarian and allergen-free. For more information about Setria® Glutathione, visit

About Sustamine® L-Alanyl-L-Glutamine

Sustamine® L-Alanyl-L-Glutamine, manufactured by Kyowa Hakko Bio Co., Ltd., is a clinically studied and patented form of L-Alanyl-L-Glutamine. Sustamine is a stable dipeptide of L-Alanine and L-Glutamine and is more easily absorbed by the body than complex protein molecules. This makes Sustamine a highly effective ingredient for hydration, endurance and recovery.* Sustamine is manufactured through a patented fermentation process to yield high quality and high purity.  Vegetarian, allergen-free and the only GRAS L-Alanyl-L-Glutamine, Sustamine is also tasteless, odorless, and stable in liquids. For more information on Sustamine, visit:

About Kyowa Hakko Bio Singapore

KYOWA HAKKO BIO SINGAPORE PTE LTD is the Southeast Asia office for KYOWA HAKKO BIO an international health ingredients manufacturer and world leader in the development, manufacturing and marketing of pharmaceuticals, nutraceuticals and food products. Kyowa is the maker of branded ingredients including Cognizin® Citicoline, Pantesin® Pantethine, Setria® Glutathione, as well as Sustamine® L-Alanyl-L-Glutamine. For more information visit or email

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