Kyowa Hakko USA Announces GRAS Self-Affirmation for the amino acid L-Citrulline

L-Citrulline helps support nitric oxide metabolism and protein synthesis

Kyowa Hakko U.S.A., Inc. (Kyowa Hakko USA), the wholly owned subsidiary of KYOWA HAKKO BIO CO., LTD. (Kyowa), has announced it has completed GRAS (Generally Recognized As Safe) self-affirmation for the valuable amino acid L-Citrulline.

L-Citrulline is an amino acid that plays an important role in nitric oxide (NO) metabolism and regulation. L-Citrulline is converted to L-Arginine in the body to support L-Arginine and NO levels. Increased production of NO promotes vascular dilation which improves oxygen and blood circulation throughout the body. L-Citrulline is also expected to relieve muscle fatigue through ammonia elimination. Antioxidant action and heart protection are also known.

“We are extremely proud to announce GRAS for our amino acid L-Citrulline, and look forward to working with manufactures to incorporate it into foods and beverages,” said Dr. Toshikazu Kamiya, President & CEO of Kyowa Hakko USA.

L-Citrulline is preservative-free, allergen-free, and contains no artificial flavors or colors. Manufactured in the U.S. using a proprietary fermentation process, L-Citrulline is an ultra-pure amino acid that carries the Kyowa Quality logo, ensuring that this ingredient is backed by our commitment to the highest manufacturing standards.

L-Citrulline will be marketed by Kyowa Hakko USA as a food ingredient in the United States for use at levels of 275 mg of L-Citrulline/serving up to a maximum of 2000mg/day in various food products, such as beverages and beverages bases; grain products and pastas; and milk products.

About Kyowa Hakko USA
Kyowa Hakko USA is the North American sales office for Kyowa Hakko Bio Co. Ltd., an international health ingredients manufacturer and world leader in the development, manufacturing and marketing of pharmaceuticals, nutraceuticals and food products. Kyowa is the manufacturer of amino acids and related compounds as well as Cognizin® Citicoline, Pantesin® Pantethine, Setria® Glutathione, as well as Sustamine® L-Alanyl-L-Glutamine. For more information visit www.kyowa-usa.com.

« Back