New York, NY – Deborah Yurgelun-Todd, Ph.D., Director of the Cognitive Neuroimaging Laboratory at The Brain Institute at The University of Utah, presented new scientific data on Kyowa Hakko's branded brain health ingredient Cognizin(R) at the SupplySide Science Tour held January 24, 2011, in Irvine, Calif. She highlighted results of a six-week study conducted at McLean Hospital, a Harvard Medical School affiliate located in Belmont, Mass., designed to measure and visualize the functional effects of Cognizin on various facets of brain function.
On the first day of testing, 16 healthy subjects aged 40 - 60 years underwent functional Magnetic Resonance Imaging (fMRI) while completing both the Stroop task, which is designed to measure attention and reaction time, and the Morris Water Maze task, which examines spatial memory. Subjects were then given a daily oral dose of either 500 or 2000 mg of Cognizin for six weeks before a second imaging protocol was conducted.
After completion of the second fMRI imaging test, increased activation was seen during completion of the Stroop interference task. This was accompanied by improved accuracy in generating correct responses. These results indicated that use of Cognizin resulted in a better, more accurate performance, accompanied by increased brain metabolism. Increased activation was seen during completion of the second Water Maze test as well. This was accompanied by increased time spent in the correct quadrant. These results indicated that use of Cognizin resulted in better spatial memory retrieval, in addition to increased brain metabolism. Results were nearly identical for individuals receiving 500 mg and 2000 mg of Cognizin, confirming that statistically significant improvements in attention, focus, memory and recall can be achieved at dosing levels of 500 mg.
"Neuroimaging data demonstrated increased regional brain activation, which was related to increased concentration, greater ability to focus and improved accuracy on cognitive tasks after subjects received Cognizin," noted Dr. Yurgelun-Todd. "Greater performance on a spatial memory task was also observed."
Cognizin Citicoline is a natural, water-soluble brain health ingredient, and is a well-established part of the cognitive health category. Vast research indicates this safe and effective branded compound helps protect neural tissue from free radical damage. It also supports brain performance by enhancing metabolism and healthy activity. Unlike other single-action ingredients for brain health, Cognizin is multi-functional. It has been shown to benefit individuals affected by memory loss, mood/behavioral disorders, mild cognitive impairment and certain vision disorders. Cognizin is also highly stable, ultra-pure, allergen-free and has self-affirmed GRAS status, allowing it to be used in a variety of functional food and beverage applications, in addition to supplements. For more information on Cognizin visit www.cognizin.com.
Kyowa Hakko is an international health ingredients manufacturer and world leader in the development, manufacturing and marketing of pharmaceuticals, nutraceuticals and food products. Kyowa is the maker of branded ingredients including Cognizin(R) Citicoline, Hydrafend(TM) Hyaluronic Acid, Lumistor(R) L-Hydroxyproline, Setria(R) Glutathione, Kyowa CoQ10(TM) as well as Sustamine(TM) L-Alanyl-L-Glutamine.
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Courtney Jacobs Morton
Integrated Marketing Group
P: 801-538-0777 x102